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Results for "

( )-Ajmaline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) ROS Kinase (1) Sodium Channel (1)
By Research Areas:	Cardiovascular Disease (1) Infection (1)

3

Inhibitors & Agonists

2

Natural
Products

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Ajmaline* Cardiorythmine; (+)-Ajmaline	Sodium Channel	Cardiovascular Disease
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .

Secologanin	Others	Others
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin .

HS-291	ROS Kinase Bacterial	Infection
HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb .

Species:	Virus (2) Human (1)
Tag:	His (2) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	NS3 protease Protein, HCV (GST) Hepatitis C virus (HCV-1a) NS3 protease / helicase immunodominant region Protein ( GST)	Virus	E. coli
	NS3 protease Protein is a zinc-dependent serine protease. NS3 needs to bind to the viral protein NS4A to enable additional conformation changes that enhance activity and appropriate intracellular localization. NS3 protein induces Caspase-8-mediated apoptosis independently of its protease or helicase activity. NS3 protease Protein, HCV (GST) is the recombinant Virus-derived NS3 protease protein, expressed by E. coli , with N-GST labeled tag. The total length of NS3 protease Protein, HCV (GST) is 104 a.a., with molecular weight of ~37.9 kDa.

	VSTM2A Protein, Human ( E84K, HEK293, His) V-set and transmembrane domain-containing protein 2A; VSTM2	Human	HEK293
	VSTM2A Protein, a key player in early white and brown preadipocyte differentiation, actively promotes adipogenic commitment by upregulating the transcription factor PPARG. This regulatory role operates within a BMP4-dependent signaling pathway, highlighting intricate molecular mechanisms in differentiation. Additionally, VSTM2A functions as a homodimer, suggesting involvement in complex protein-protein interactions critical for its regulatory activities. VSTM2A Protein, Human ( E84K, HEK293, His) is the recombinant human-derived VSTM2A protein, expressed by HEK293 , with C-6*His labeled tag and E84K mutation. The total length of VSTM2A Protein, Human ( E84K, HEK293, His) is 220 a.a., with molecular weight of 38-40 kDa.

	HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) Influenza A H3N2 (A/Victoria/208/2009) Hemagglutinin / HA Protein (sf9, His)	Virus	Sf9 insect cells
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) is 530 a.a., with molecular weight of ~59.2 kDa.

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